Tuesday, March 29, 2011

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Patarroyo is the formula that will create vaccines against all infectious diseases



The discoverer of the first synthetic vaccine against malaria, which he donated to the WHO, announced their discovery in the journal 'Chemical Reviews'
Health tumor.
What is a synthetic vaccine?
A vaccine that does not use or living organisms or dimmed to produce immunity. This is the molecule used by the infectious agent to bind to host cells and produce the enferemedad. So although it is called VACCINE generate leads as defenses to an infectious process. does not produce side effects that produce the vaccines so far have been used, calls biological vaccine
Bogotá. (EFE) .- The
Colombian scientist and discoverer of the first
vaccine against malaria
, Manuel Elkin Patarroyo
, found the chemical principles that will create , giving him the backing of the scientific world . It is "a decalogue of principles, rules, which when applied can produce vaccines against various diseases that exist in the world, so we can cover virtually the 517 infectious diseases, "he said.
synthetic vaccines to prevent virtually all the



infectious diseases in the world.

After more than 30 years of research, Patarroyo reported the findings in an interview with Efe


after it was released today by the U.S. magazine Chemical Reviews
The scientist found these principles, that would prevent future millions of deaths on the planet from the discovery of its first vaccine against malaria, in 1986, and then develop the second generation drug coverage above 90 percent in trials with monkeys.
Of these 517 diseases, only fifteen have vaccine, why that Patarroyo and his team at the Foundation Institute of Immunology of Colombia (FIIC) faced "the problem from the point of view chemistry, "a landmark in science as the only existing developed from biology. After entering the microbe in the body through mosquito bites and reached the liver," recognized the proteins or molecules the parasite uses to attach to cells and then infect you find out its chemical structure fragments after them, "said the doctor acknowledged." That, per se, is a great discovery, but these fragments can not be used as vaccines because defense system is blind and can not see, "he added, explaining that the blindness of the immune system is what allows the germs to hide in the body. The solution was to modify the fragments through chemistry, ie create synthetic proteins identical to those of the only parts of the microbe capable of adhering to red blood cells and then change the order of the components. This formula makes molecules visible before unrecognizable by the immune system.
scientist explains in simple words: "turn back the fingers of the hands of the bug" to make them visible, referring to the only parts that attach to the cells because the rest of the parasite is not contagious and therefore not serves to prepare the vaccine, by failing to ensure the prevention of the disease hundred percent. "So the molecule (copied and then chemically modified) becomes highly producing antibodies, defenses, and may be used as a vaccine," he added.
While these findings from the study of malaria, Patarroyo has shown that these principles are used to offset other infectious ailments. The Columbian works primarily with the microbe of malaria because, among other reasons, is one of the most destructive for the speed with which it spreads into the body: "there are about 500 million cases per year and of these nearly three die, mostly children under five in Africa. " After the latest discovery, you can apply to tuberculosis, human papillomavirus, dengue, hepatitis C or leprosy, to name some of the most common diseases among the five hundred of infectious, "which annually cause the death total to 16 million people," said the scientist . Patarroyo discovered the first vaccine against malaria in 1986, called SPF-66, and after testing for over 50,000 individuals from different countries are checked for effectiveness between 30 and 50 percent. In 1996, when he gave the patent to the World Health Organization (WHO), ceased to apply to plunge into the research and find their one hundred percent effective. Now 25 years later and has the second generation of this vaccine, which it calls COLFAVAC and has proven effective over 90 percent in monkeys. "We will begin human trials and we are absolutely confident that we will have the same results", she said, finding, even after years of research, the body of Amazonian monkeys used are identical to that of men. The Colombian has received numerous awards throughout his career, as the Prince of Asturias, Medaille Robert Koch Prize in International Latin American Fernando D. Pulmonology Gomez, Leon Bernard WHO and Principe de Viana of Solidarity.

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